Assay development/ Screening

Our Services

    • Tailored assay development focused on specific biological targets, disease pathways, or cellular phenotypes.

    • Expertise across biochemical and cellular assays.

    • Designed to support screening campaigns across a broad range of therapeutic modalities, including small molecules, biologics, nucleic acid based agents and emerging drug classes.

    • Automated liquid handling systems to enable high throughput dispensing and flexible automation workflows, ideal for screening applications across diverse assay formats

    • Miniaturised and scalable formats (96-, 384-, 1536-well) to enable cost-efficient hit discovery.

    • Broad portfolio of functional cellular assays including cell proliferation, viability, reporter gene expression, and cytokine profiling.

    • Biochemical formats include enzyme activity, protein-protein interactions, and receptor-ligand binding.

    • Customisable systems for disease-relevant models including oncology, inflammation, neurodegeneration, and infectious disease.

    • Expertise in precise genome modification using CRISPR/Cas9 and related systems, enabling targeted knockouts, knock-ins, and site-specific point mutations.

    • Custom-engineered cell lines, organoids, or model systems tailored to reflect disease-relevant genotypes, resistance mechanisms, or therapeutic targets.

Capabilities

With expertise in assay design, optimisation, and validation, our team supports drug discovery, diagnostics, and biomarker development through precise, scalable, and reliable testing solutions.

FMI Capabilities

Custom assay design tailored to biological targets or pathways

  • High-throughput screening using automated platforms

  • Cell-based and biochemical assays for functional and mechanistic studies

  • Assay validation and quality control in line with industry standards

  • Data analysis and hit triage for lead identification and profiling

Team

Dr Kienan Savage

Academic Lead

DNA damage/response repair mechanisms

Dr Claudia Hamilton

Research Fellow

Cell death pathways/ small molecule screening

Dr. Catherine Higgins

Senior Research Fellow

Cell death pathways/ small molecule screening

Dr Sarah McFetridge

Research Fellow

Bacteriology/ Immunology

Dr Andrew Shaw

Research Fellow

Metabolism/ Epigenetics

Our technology