Instruments and Equipment
Cyto-Mine® Chroma
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Cyto-Mine® Chroma is a multiplexing-capable, fully-automated single cell analysis platform that can encapsulate, analyze, sort, and dispense viable single cells.
Leveraging picodroplet technology, single cells are encapsulated in tiny volumes of liquid (e.g. cell culture media). Cyto-Mine® Chroma automates incubation of the cells and cellular output, proliferation, and/or interactions can be measured using standard fluor-based assays.
The automated system screens millions to tens of millions of viable single cells and simple controls allow users to select and dispense targeted desired cells for downstream outgrowth
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Save time
Functionally analyze millions to tens of millions of single viable cells in a single day shortening standard workflows by months
Enhanced detection
Able to detect secreted cellular products
Easy to use
Simple-to-use workflows eliminate the need for extensive training on overly complex systems
Flexible
Multiple assays provide flexibility in use cases and integration in your research pipeline
Automated
Automate tasks that require manual labor and handoff between multiple pieces of equipment
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CellInsight™ CX7 LZR Pro High Content Screening Platform
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The Thermo Scientific™ CellInsight™ CX7 LZR Pro High Content Screening (HCS) Platform is an advanced, laser-based automated cellular imaging and analysis system designed for high-throughput, high-content applications in life sciences
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Multiplexing capabilities
7-color laser excitation (405, 450, 488, 561, 594, 647, 785)
User friendly software
HCA Studio Cell Analysis Software – with 40 ready-to-go assays.
Incorporates Amira software for advance 2D-5D bioimaging workflows including performing z-stacks and generation of 3D renders on AMIRA software
High resolution images
Photometrics high-resolution fluorescent camera (sCMOS)
High-resolution, thermoelectrically cooled to -20°C
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Echo 650 Acoustic liquid handler
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The Echo 650 Acoustic Liquid Handler by Beckman Coulter Life Sciences is a cutting-edge, tip-less liquid handling system that utilizes acoustic energy to transfer nanoliter-scale volumes with exceptional precision and accuracy. This contact-free technology is ideal for applications requiring assay miniaturization, high-throughput screening, and sensitive sample management
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Workflow automation
Capable of transferring nL droplets with a maximum transfer rate of 1 μL/sec
Time saving
Enable miniaturization of assays saving time and reducing consumable costs
User friendly
Echo plate reformat (EPR) and Echo dose response (EDR) software applications to easily control the system and customise plate layouts
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LI-COR Odyssey® M Imaging System
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The LI-COR Odyssey® M Imaging System is a versatile, high-resolution imager designed for multiplexed detection of fluorescence and chemiluminescence across a wide range of biological assays. It integrates advanced optics, multiple imaging channels, and user-friendly software to support applications such as Western blotting, ELISA, in-cell assays, and tissue imaging.
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High-Resolution Imaging:
Capable of imaging multiple sample types including membranes, plates, tissue slides and gels simultaneously
Multiplexing Capability:
Integrated lasers and filters to enable the use of multiple wavelengths in a single read.
19 detection channels allowing flexibility to conduct a wide range of plate-based assays
Wide Dynamic Range:
Provides a dynamic range exceeding 6 logs for both fluorescence and chemiluminescence
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Sartorius Incucyte® S3
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Sartorius Incucyte® S3 Live-Cell Analysis System is an advanced imaging platform designed for real-time, automated monitoring of live cells within a standard tissue culture incubator. Observe and quantify dynamic cellular processes over extended periods without disturbing the cell environment.
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Multi-Channel Imaging:
Equipped with HD phase contrast and two-colour fluorescence (green/red)
Automated Objective Turret:
Features 4X, 10X, and 20X objectives on an automated turret.
High Throughput Capacity:
Accommodates up to six microplates simultaneously
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4D-Nucleofector® X Unit
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An advanced electroporation platform developed by Lonza for delivering nucleic acids (like DNA, RNA, or CRISPR components) directly into the nucleus of hard-to-transfect cells enabling highly efficient transfection of primary cells and cell lines.
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Wide Cell Number Range:
Supports transfection of cell numbers from 2 × 10⁴ to 2 × 10⁷, accommodating various experimental needs
High Throughput Capability:
Enables 16–32 reactions per minute using 16-well strips and 20–26 reactions per minute with 100 µL vessels, enhancing productivity.
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Clariostar® Plus multimode plate reader (BMG)
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The CLARIOstar® Plus from BMG LABTECH is a high-performance, multi-mode microplate reader designed to offer exceptional flexibility, sensitivity, and speed for a wide range of assays. It integrates advanced technologies to support various detection modes and is particularly suited for assay development.
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Advanced Detection Technologies:
Equipped with patented LVF Monochromators™, highly sensitive filters, and an ultra-fast UV/Vis spectrometer.
Enhanced Dynamic Range (EDR):
Provides the largest dynamic range with no manual intervention, allowing detection of both low and high signals in the same run.
Ultra-Fast Data Sampling:
Capability to perform 5 simultaneous multiwavelength reads in one well
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Pherastar FSX multimode plate reader (BMG)
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The PHERAstar® FSX by BMG LABTECH is a state-of-the-art multimode microplate reader, engineered for high-throughput screening (HTS) and assay development. It combines exceptional sensitivity, speed, and flexibility to accommodate a wide array of applications in drug discovery, molecular biology, and biochemical research.
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High-Density Plate Compatibility:
Capability to perform 5 simultaneous multiwavelength reads in one well
Integrated plate stacker for up to 50 microplates to enable high throughput screening
Advanced Well Scanning:
Capability to perform 5 simultaneous multiwavelength reads in one well
Time resolved fluorescence (TFR) with a pair of matched photon counting detectors operating over a range from 230-900nm dedicated fir TRF and TR-FRET assays
Simultaneous dual emission detection system in all well-read modes ideal for double emission assays such as FRET, TR-FRET, BRET and Alphaplex
Temperature Control:
Incorporates an Advanced Assay Stability (AAS) system, maintaining temperatures from 18°C to 45°C to ensure optimal assay conditions.
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ISOLUTE® Single Fritted Columns
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ISOLUTE® Single Fritted Columns by Biotage are versatile filtration tools designed for sample preparation workflows, particularly in solid-phase extraction (SPE) and filtration applications.
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Pre-Fitted Frits:
Each column comes with a single frit made from either polyethylene (PE) or polytetrafluoroethylene (PTFE), eliminating the need for manual frit insertion and ensuring consistency across samples.
Variety of Porosities:
Available frit porosities include 5 µm (PTFE), 10 µm (PE), and 20 µm (PE),
Stackable Design:
Designed to be used as standalone filtration units or stacked above SPE columns to increase reservoir volume, facilitating the processing of larger sample volumes without the need for additional equipment.
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Genevac EZ-2 40 Series Centrifugal Evaporator
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The Genevac EZ-2 system is used to concentrate both compound library reaction and post prepLC samples to dryness.
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No bumping
Dri-Pure® anti-bumping technology – protects samples from foaming and cross-contamination
Easy to use
Touchscreen interface allows simple set-up for even the most inexperienced user
Pre-programmed methods for low and high boiling solvents, HPLC fractions and extra dryness options.
Compact design
Saves valuable lab space without compromising on quality
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Monowave 450
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The Anton Paar Monowave product line is a series of high-performance monomode microwave reactors designed for small- to medium-scale microwave synthesis.
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Fast and effective
24 sequential reactions, unattended
Adaptable
Can run reactions 500 mg to 3 g scale for intermediate synthesis via use of 8 position 30 mL reaction carousel
Live analysis
In built camera system allows for the monitoring of on-going reactions
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Biotage Isolera System
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The FMI Chemistry lab has two Biotage Isolera systems designed to handle purification tasks.
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Large scale purification
Used to purify intermediates on 100 mg to 5 g scale
Pre-packed normal phase columns in 10, 25 and 50 g sizes
Automated
UV triggered automate fraction collection
Adjustable UV detection wavelengths via method set-up
Can queue up to 4 columns via automated software
Easy to use
Easy to use software via touch screen interface
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Sepiatec preparative HPLC system
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The SFC-50 from Sepiatec is a compact and easy-to-use chromatography system for preparative separations on small columns by means of supercritical fluid chromatography (SFC).
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The Sepiatec preparative HPLC system supports the automated purification of final compounds and compound libraries on 10-50 mg scale.
Green technology supports the purification of compounds using liquid CO2 to reduce the amount of solvent required via traditional methods
Can queue up to 60 samples for purification using either individual or group methods.
UV/ELSD triggered automated collection of compounds
Use of reverse columns to support column purification
Use of touch screen to set-up methods and sample lists
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Agilent Single Quadrupole LC/MS
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The FMI Chemistry lab has 2 state-of-the-art Aligent LC-MS systems to support reaction monitoring, intermediate and final compound analysis
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High Sensitivity with Agilent Jet Stream Technology:
Uses super-heated sheath gas to focus the ion stream, enhancing sensitivity and enabling sub-picogram detection limits.
Fast Scan Speeds:
Allows for rapid data acquisition and compatibility with ultra-high-performance liquid chromatography (UHPLC) systems.
Multiple Ionization Modes:
Support for electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI)
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Teledyne ACCQ Prep HP150 HPLC
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The ACCQPrep HP150 is a preparative high-performance liquid chromatography (HPLC) system engineered for simplicity and performance. It bridges the gap between traditional flash chromatography ease-of-use and the precision of full analytical HPLC systems
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Wide Flow Rate Range:
Operates from 1 to 150 mL/min, accommodating both analytical scouting and preparative methods
High Operating Pressure:
Supports pressures up to 6,000 psi, enabling the use of high-efficiency columns and faster flow rates.
Integrated Detection Options:
UV and UV-Vis Detection: Variable wavelength detection
Evaporative Light Scattering Detector (ELSD): For detecting compounds lacking chromophores
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Bruker timsTOF Pro 2
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The Bruker timsTOF Pro leverages Trapped Ion Mobility Spectrometry (TIMS) integrated with Quadrupole Time-of-Flight (QTOF) detection, enabling advanced separation, sensitivity, and speed
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•Current mass spectrometers in the omics field are limited due to speed, sensitivity and resolution, posing a challenge to mapping coverage of proteomes or metabolomes in biological samples.
•Trapped ion mobility spectrometry (TIMS) enables the addition of a further separation method along with HPLC to increase peak capacity by resolving sample complexity. It also works to accumulate and concentrate ions of a specified m/z to increase speed and sensitivity.
•Ions are separated using TIMS, eluted and then detected in the quadrupole time of flight (QTOF).
•This enables the parallel accumulation serial fragmentation (PASEF) to serially fragment ions. This increases MS/MS speed and sensitivity, requiring minimal sample amounts.
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Bruker nanoElute Liquid Chromatography
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The nanoElute family from Bruker are a series of nanoflow liquid chromatography (nLC) systems designed for highly sensitive LC–MS workflows, especially in proteomics, including single-cell and high-throughput applications.
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Built for reliability and easy setup, with an integrated, user-friendly interface.
Supports trap columns, self-optimizing separations, proactive maintenance, and direct injection.
Technical specs:
Split-free flow from single-stroke piston pumps (1300 µl)
Dual-column options
Pressure range: 0–1000 bar
Flow range: 50–2000 nl/min with integrated flow sensors
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Integra Viaflow Assist Plus
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Designed to streamline routine lab tasks, ASSIST PLUS brings full workflow automation.
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Ergonomic and consistent performance
By automating repetitive pipetting, it helps prevent repetitive strain injuries and dramatically improves reproducibility by enforcing consistent tip angles, immersion depths, speeds, and targeting
Flexible and future-ready
Uses INTEGRA’s multichannel pipettes for a wide range of volumes (0.5–1250 µl)
Easy programming through touch or software
Predefined protocols set up right on the pipette with its intuitive Touch Wheel interface
Broad compatibility with labware
Supports a wide variety of labware, including tubes, microplates (6- to 384-well), and reservoirs, in both orientations.
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Opentrons Robot
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Open-source liquid handling robots that automate routine lab pipetting
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•Bench top liquid handler
•Automates sample processing before introduction to the mass spectrometer.
•Loads samples onto Evotips which pairs with the Evosep LC
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Agilent 1260 Infinity III Bio HPLC
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The 1260 Infinity III Bio-Inert is a high-performance liquid chromatography platform specifically designed for the analysis of large biomolecules—such as monoclonal antibodies and proteins. It offers a corrosion-resistant, metal-free flow path to preserve biomolecule integrity and extend column lifespan.
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•Designed to automate HPLC processes to reduce operator error and ensuring reliable HPLC results.
•This system is compatible with our timsToF instruments.
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Evosep Eno
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The Evosep One is a specialized liquid chromatography solution tailored for clinical proteomics, high-throughput analysis, and standardized workflows. It emphasizes ease of use, reliability, and integration with downstream mass spectrometry
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•Standardized platform designed to integrate sample preparation with LCMS analysis to streamline and optimize workflow.
•The Evotip is a precision technology device with extremely high efficiency enabling desalting to become integrated with LC-MS sample introduction.
•The Evosep will elute all peptides, leaving contaminants and larger hydrophobic molecules on the Evotip which helps to preserve the column lifetime and reduce blockages.
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ÄKTA pure™ 25T chromatography system
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The ÄKTA 25 T is a high-performance chromatography system designed for protein purification, process development, and scalable workflows. It prioritises precision, reproducibility, and seamless integration with downstream analytical techniques.
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Precise and flexible flow control
Dual-piston pumps (0.001–25 ml/min) allow highly accurate flow rates, suitable for both small- and large-scale purifications.
Enhanced monitoring and reliability
Integrated system pressure, UV, conductivity, and pH monitoring ensure reproducible results and reduce risk of errors.
Automated sample and buffer handling
Inlet valves with air sensors and automatic switching between buffers and samples simplify workflows and minimise manual intervention.
Software-driven workflow control
UNICORN 7 workstation provides intuitive software control for method setup, monitoring, and data analysis, enhancing usability and reproducibility.
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Biacore 1K+
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The Biacore 1K+ Surface Plasmon Resonance (SPR) System is a next-generation, label-free interaction analysis platform designed to deliver high-quality biomolecular binding data with exceptional sensitivity and throughput. Engineered for life science research, drug discovery, and translational projects, this SPR instrument provides real-time insights into the kinetics and affinity of molecular interactions without the need for labelling. Its user-centric design and flexible configuration support a broad range of applications, from early-stage screening to advanced characterisation of proteins, small molecules, and complex biological samples.
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The Biacore 1K+ SPR system delivers high-quality binding data with enhanced flexibility and high analytical capacity.
Serial injection across six flow cells significantly reduces analyte consumption—by at least 40% for small antibody screening—compared with four-flow-cell SPR systems.
Twice the analytical capacity of the Biacore 1K system, enabling the loading of more than 870 samples and reagents using two microplates and two reagent racks.
Minimised hands-on time through queue-based operation and four independent buffer inlets, allowing experiments to run unattended for up to 72 hours.
Advanced sample injection tools provide maximum experimental flexibility, supporting mutant specificity and selectivity studies, buffer screening, and competition assays.
Automated and standardised data evaluation, including built-in data quality checks, export functions, and graphical reporting, accelerates time to results.
Highly versatile platform suitable for a broad range of applications, molecule types, and sample complexities—from small fragments to large viruses.
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Mabtech ASTOR™
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The Mabtech ASTOR™ is a dedicated ELISpot plate reader developed to provide reliable, accurate, and user-independent analysis of immune cell responses. ASTOR delivers robust spot quantification while maintaining a simple and intuitive workflow.
ASTOR integrates proprietary RAWspot™ technology with optimized hardware to ensure precise identification and enumeration of spot-forming units. This enables consistent detection of cytokine- or antibody-secreting cells at the single-cell level which is an essential requirement in immunological research, vaccine development, and cellular assay applications.
The system is engineered for ease of use, incorporating pre-calibrated settings and automated alignment to minimise operator input. Combined with the Mabtech Apex™ software platform, ASTOR allows users to move efficiently from plate loading to analysed data, reducing variability and improving reproducibility across experiments.
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High-precision spot quantification (RAWspot™ technology)
Processes uncompressed raw image data instead of compressed formats like JPEG or TIFF. This allows for highly accurate identification of spot centers and enables quantification of up to approximately 3,000 spots per well, even in dense assays.
Simplified, efficient workflow
Designed for a “load-and-run” approach with minimal user intervention.
It features a self-calibrating XY stage and fixed-focus optics, which support reliable positioning and repeatable measurements.
Reliability and regulatory compliance
Supports long-term performance verification using Mabtech Performance Qualification (PQ) plates, allowing users to routinely confirm instrument accuracy and stability.
Meets regulatory requirements, including FDA 21 CFR Part 11.
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